Our lab aims to understand the molecular underpinnings controlling synaptic function to ultimately dissect how its dysregulation affects brain physiology and impacts human disease. We use cutting-edge optical tools to examine diverse aspects of the biology of synapses to develop a detailed picture of the molecular mechanisms controlling synaptic transmission. Our overarching goal is to provide actionable knowledge that can be used to design better strategies for screening, prevention, and treatment of human diseases. We collaborate with physicians at the Pitié-Salpêtrière Hospital to study human brain physiology and to increase our understanding on the synaptic molecular drivers of epilepsy and other neurological diseases.