About
During my PhD in C. Gauthier-Rouvière lab (2003-2007), I combined biochemical and cell biology approaches to study the dynamics of cadherin-mediated cell-cell adhesion. I then moved to the USA in G. Bokoch lab (2008-2012) for a postdoc where, using cutting edge microscopy techniques, I studied how reactive oxygen species modulate actin dynamics to promote cell migration and how they contribute to cancer cell invasiveness. Finally, I joined the lab of B. Delaval (2012-2017) where I used different systems (2D and 3D cell culture) to study the role of ciliary transport proteins during cell division and their contribution to kidney diseases.
Team info
Scientific info
Research domains |
adhésion/interactions cellulaires |
|
cycle cellulaire |
|
migration |
|
morphogenèse |
|
signalisation |
|
trafic intracellulaire |
Organelle/Compartment |
centrosome |
|
cils et flagelles |
|
cytosquelette: microtubules |
|
cytosquelette: actine |
|
kinetochore |
|
membrane plasmique |
Techniques |
biosenseurs |
|
culture 3d |
|
imagerie confocale |
|
imagerie frap, flim, fret, etc |
|
imagerie spinning disk |
|
imagerie tirf |
|
videomicroscopie |
Cell Models |
lignees cellulaires |
|
zebra fish |