About
Dr. Hanein was educated at the Weizmann Institute, Israel. Dr. Hanein completed training as a Fulbright postdoctoral fellow at Brandeis University with David DeRosier, the founding father of three-dimensional image reconstruction techniques via electron microscopy. Dr. Hanein is a PEW Innovation Fund Investigator. She is directing the Structural Studies of Macromolecular Machines in Cellula Unit (ESMMC) at Institut Pasteur. With her team, Dr. Hanein specializes in developing ways to directly see inside our bodies the tiny, nanomachines that work tirelessly to allow us to fight intruders, to see and hear, to heal bruises, cuts and diseases, to run and practice yoga and to be happy. To visualize these nano machines, her talented unit members employ and operate a versatile and unique set of high-end electron microscopes instrumentations including Titan Krios, Glacios and Aquilos Dr. Hanein commissioned for Institut Pasteur in 2019. The capabilities of these microscopes allow to obtain a quantitative representation of life at the atomic scale. This holistic approach to research is at the interfaces between structural biology, cell biology, systems biology, and engineering science and at the forefront of exciting new developments bridging cryogenic electron microcopy, cell biology, and systems biology which carries high impact in both medicine and basic biological research.
Team info
Scientific info
Research domains |
3R |
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adhésion/interactions cellulaires |
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apoptose |
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biologie des systèmes |
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migration |
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morphogenèse |
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pathogènes/parasites |
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transduction du signal |
Organelle/Compartment |
cytosquelette: microtubules |
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cytosquelette: actine |
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cytosquelette: filaments intermédiaires |
Techniques |
biophysique |
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cryo-me |
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microscopie electronique |
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nanoparticules, quantum dots |
Cell Models |
cellules primaires |
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cellules souches adultes |
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cellules souches embryonnaires |