A post-doctoral fellowship in renal physiology is offered in the Laboratory of Tissue Biology and Engineering Therapy (CNRS, LBTI, UMR5305) in Lyon. The candidate will work on scientific projects related to the study of molecular and cellular mechanisms involved in the adaptation of the kidney to ionic balance perturbations (regulation of the acid-base state and of sodium and potassium balances). These adaptive mechanisms are crucial for the regulation of blood pressure, kalemia and blood pH.
Activities
This project requires the use of genetically modified mouse models allowing the tracing of renal cell populations in vivo. Several cell culture models will also be generated in the laboratory to understand the mechanisms that allow renal cell plasticity. He will also study the role of a receptor tyrosine kinase in the adaptive response of the kidney to ionic balance perturbations.
Qualifications
Applicants must have a PhD and a maximum of two years of postdoctoral experience after their last degree. Applications from PhD students shortly before their thesis defense will also be considered.We are looking for a candidate who has already demonstrated scientific output.
The candidate must show extensive experience and knowledge in either:
1) in renal physiology with study of renal function or
2) in epithelial cell culture with autonomy in the manipulation and analysis of complex cell models (organoids, 3D cell culture).
The successful candidate will have good verbal and written communication skills, allowing him/her to consider writing scientific articles.
Work context
The project is developed in the SKIN team of LBTI which is also interested in other epithelial cells such as skin.
This offer is funded by an ANR project (FateForA https://anr.fr/Projet-ANR-21-CE14-0040) which is developed in collaboration with a research group in Paris led by G. Crambert.
The laboratory and our team can propose you to develop your autonomy and to have the opportunity to apply for research funding on your behalf allowing you to develop your own ideas.
Constraints and risks
The laboratory is located in a ZRR zone (zone à régime restrictif). The profile of the candidate will be examined by the services of the Ministry of Research and the final decision of recruitment will be given after this opinion.
The contract can start in April but should not exceed 01/09/2023.
A level 1 or 2 training in animal experimentation would be a plus
Additional Information
Applicants should submit a cover letter, several references and a CV via the CNRS jobs site (https://emploi.cnrs.fr/Offres/CDD/UMR5305-NICPIC-005/Default.aspx). You can send your questions about this job offer to Nicolas Picard, CNRS Research Associate (nicolas.picard@ibcp.fr)
