Our group is interested in Cadherin biology and in their role during collective cell invasion. We have developed and validated a model system in which we induce collective cell migration by expressing P-cadherin in C2C12 myoblasts, satellite cells which function as muscle progenitors and do not express P-cadherin. P-cadherin, a cell-cell adhesion protein expressed in …

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We are looking for a highly motivated and team oriented postdoctoral candidate to work on the role and the regulation of the Polo-like kinase during mitotic entry using the early C. elegans embryo as model system. The Polo-like kinase Plk1 is an evolutionarily conserved serine-threonine kinase that plays a critical role during mitosis. Plk1 regulates …

Continuer à lire “Post-doctoral position – Institut Jacques Monod PARIS”

Nanotechnology has quickly swept across the medical field by proposing sometimes unprecedented solutions at the furthest limits of current treatments, thereby becoming central to diagnosis and therapy, notably for the regeneration of tissue. A current challenge for regenerative medicine is to create a cohesive and organized cellular assembly without using an external supporting matrix. This …

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Sujet de thèse 2018-2021, Financement MESR Laboratoire STIM, équipe 4CS, Direction Nicolas Bourmeyster (Co-direction Bruno Constantin) Régulation des complexes protéiques autour des canaux calciques par les GTPases de la famille Rho

The team of I. Maridonneau-Parini at the Institute of Pharmacology and Structural Biology (IPBS) is looking for a postdoctoral candidate (for Sidaction application) in charge of deciphering the molecular mechanisms involved in cell-to-cell transfer of HIV-1 to human macrophages and osteoclasts. In addition to T lymphocytes, macrophages and osteoclasts are cell targets for HIV-1 that …

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Désolé, cet article est seulement disponible en Anglais Américain.

Manipulating the redox status in cancer cells to increase or restore the sensitivity towards chemo- and radiotherapies Project: The main objective of this project is to test the additive/synergistic effects of proteasome inhibitors or radiation in combination with molecules that modify the redox status of tumor cells by generating ROS (reactive oxygen species). Anti-cancer therapies …

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Désolé, cet article est seulement disponible en Anglais Américain.

Ce poste d’ingénieur/docteur pour la valorisation du projet BioactiveCoatings  (Films biomimétiques comme revêtements de plaques multipuits) bénéficie d’un financement dans le cadre de la SATT LINKSIUM de Grenoble. Vous travaillerez au sein de l’équipe “Interfaces entre Matériaux et Matière Biologique” du LMGP (C Picart, Laboratoire des Matériaux et du Génie Physique), située au sein du …

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