À propos

The team entitled “Biomechanics of Host Parasite Interactions” has been created under the lead of I. Tardieux at the Institute for Advanced Biosciences/IAB (INSERM U1209, CNRS UMR 5309, Univ. Grenoble Alpes/UGA). Moving from the Institute Cochin (Paris), IT team continues to develop quantitative high-speed live and high-resolution static imaging to identify and characterize key early processes governing Toxoplasma parasite-host cell interactions while mostly focusing on Toxoplasma motile and invasive skills. The team has been renewed for the 2021_2026 contract by the HCERES-INSERM- CNRS and UGA, and re-entitled “Biomechanics of Host Parasite Interactions. The research IT develops is optimally integrated in a collaborative local network made of (i) physicists from the LIPhy (Laboratory of Interdisciplinary Physics), nanochemists (Department of Molecular Chemistry) (ii) parasitologists and cell mechanobiologists from IAB.

Informations concernant l'équipe

Nom de l'équipe : Biomechanics of Host-Parasite Interactions
Équipe affiliée : Oui
Site web : https://www.tardieux-lab.com/
Adresse : Building Jean Roget, 5th floor, La Tronche, 38000, Grenoble, France
Responsable(s) de l'équipe : Isabelle Tardieux

Informations scientifiques

Domaines de recherche adhésion/interactions cellulaires
mecanotransduction
migration
pathogènes/parasites
pathologies
trafic intracellulaire
transduction du signal
Organite/ Compartiment cytosquelette: microtubules
cytosquelette: actine
cytosquelette: filaments intermédiaires
enveloppe nucléaire
matrice extracellulaire
membrane plasmique
noyau
Techniques biophysique
biosenseurs
cryo-me
culture 3d
culture d’explants
imagerie confocale
imagerie haute resolution (sted, 4pi)
imagerie spinning disk
microscopie electronique
nanoparticules, quantum dots
videomicroscopie
Modèles cellulaires cellules primaires
cellules souches embryonnaires
lignees cellulaires
souris, rat