À propos
I am a US doctoral candidate in the United Kingdom. I completed a Master's degree in neuroscience studying autophagy and its potential role as a therapeutic strategy for neurodegenerative diseases and obtained a Bachelor of Arts degree in biology in the USA. Currently, as a doctoral researcher, I am working on using quartz capillary solid-state nanopores for the characterisation of amyloids for single-cell probe for functional and cytotoxic studies. So far, I have obtained robust results characterising variants of α-synuclein, β-amyloid, globular proteins, and DNA of varying topology. In addition, I also use atomic force microscopy to investigate the structure of amyloid fibrils such as variants of α-synuclein. My previous research experience includes interrogation of the biophysical binding properties of glutamate receptors, genetic engineering for systems neuroscience studies, mechanisms underlying synaptic plasticity, addiction via the limbic system VTA-NAc dopaminergic pathway, development of a novel form of optogenetic assay technique, biophysical processes governing cellular protein localization and distribution, and oxidative stress.
Informations concernant l'équipe
Informations scientifiques
Domaines de recherche |
autophagie |
|
neurobiologie |
Organite/ Compartiment |
autophagosomes |
|
endosomes/lysosomes |
|
membrane plasmique |
Techniques |
bioinformatique |
|
biophysique |
|
microscopie electronique |
|
nanoparticules, quantum dots |
|
systemes in vitro |
Modèles cellulaires |
cellules primaires |
|
modélisation in vitro |