À propos
After studying Biology in Spain, I came to Paris to do my M2 and PhD in Cellular Biology. I studied a fascinating intracellular trafic associated to primary cilia in mammal cells in the team of A. Benmerah at the I. Cochin, Paris.
Following my PhD, I wanted to jump a life-scale forward, and I chose to do a Post-Doc in Developmental Biology at the I. Curie, Paris, in the laboratory of JR. HUYNH. I studied an intriguing crosstalk between tRNAs and piRNAs molecules in genome integrity control in Drosophila ovaries.
Since 2016, I have a CNRS permanent position in the laboratory of JR. HUYNH. Strikingly, tRNAs can be cleaved into tRFs that are deregulated in several pathologies such as cancer and neurodegeneration. Nowadays, I study the roles of H2Av histone variant in Drosophila germline cells. H2av mutation leads to genome instability, transposable elements deregulation and cellular arrest, leading to sterility.
Besides, I like being involved in the life of my unit and I actively participate in several teaching activities for PSL and ENS. I am also involved in the new PSL doctoral school SDV.
Informations concernant l'équipe
Informations scientifiques
| Domaines de recherche |
apoptose |
|
cycle cellulaire |
|
développement |
|
différentiation |
|
évolution |
|
expression des gènes |
|
polarité cellulaire |
| Organite/ Compartiment |
enveloppe nucléaire |
|
noyau |
|
nucléole |
| Techniques |
bioinformatique |
|
biosenseurs |
|
cribles d’interactions |
|
imagerie confocale |
|
imagerie haute resolution (sted, 4pi) |
|
imagerie spinning disk |
| Modèles cellulaires |
cellules souches adultes |
|
drosophile |