Granted by an ERC-CoG “NeuroFish“, we are recruiting 2 postdoc researchers, 1 PhD and 1 engineer, to work on the topic of “Neurofilaments in health and neurodegenerative diseases”.
We are seeking highly motivated candidates for neuronal cytoskeleton, to work on a project aiming at fueling innovation in fundamental neurobiology and therapeutic development.
Major cytoskeletal component of neurons, Neurofilaments (NFs) provide the structural scaffold of axons and exhibit a rich functional diversity throughout the nervous system (Bomont, Curr Opin Cell Biol 2021 https://doi.org/10.1016/j.ceb.2020.10.011). Important for physiology, NF genes are mutated in several peripheral neuropathies, producing mutant-NF aggregation that is shared by most neurodegenerative diseases in human. With such fundamental and clinical significance, our project aims at decoding the roles of NFs in vivo in a physiological environment. This project has the ambition to decipher the regulation and functions of NFs, and to develop new therapeutic avenues for neurodegenerative diseases.
Details available in the attached document.
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