À propos

Dr. Christopher Thomas is a reproductive biologist and research group leader at the Developmental Biology Institute of Marseille (IBDM), France. He completed his PhD in the group of Dr. Suzanne Madgwick at the Institute for Cell and Molecular Biosciences, University of Newcastle, UK. His research focused on oocytes, the precursors to egg cells in the ovary. His findings redefined our understanding of cell cycle regulation during oocyte meiosis and revealed how oocytes repurpose key pathways to adapt to this highly specialised cell division. In 2018, Dr. Thomas joined the laboratory of Dr. Melina Schuh at the Max Planck Institute for Multidisciplinary Sciences in Göttingen, Germany, as a postdoctoral researcher. Shifting from studying single cells to a tissue-scale perspective, he set out with the challenge of live-imaging mammalian ovulation. With colleagues, he developed a groundbreaking model system that, for the first time, enabled us to visualise the entire process of ovulation in mouse ovarian follicles at cellular resolution and to describe its underlying mechanisms—a landmark achievement in reproductive biology. In 2024, Dr. Thomas established his independent research group at IBDM, Marseille. His team uses live-cell imaging and follicle culture techniques to investigate how ovarian follicles compete for the capacity to ovulate and how oocyte–follicle cell communication ensures the proper coordination of ovulation and meiosis. His pioneering approach brings ovarian biology into the modern era, tackling fundamental biological questions with significant clinical implications that, until now, we lacked the technology to address.

Informations concernant l'équipe

Nom de l'équipe : Control and dynamics of the ovarian cycle
Équipe affiliée : Oui
Site web : https://www.ibdm.univ-amu.fr/team/control-and-dynamics-of-the-ovarian-cycle/
Adresse : UMR 7288 Case 907, Luminy campus, 13288, Marseille, France
Responsable(s) de l'équipe : Christopher THOMAS

Informations scientifiques

Domaines de recherche adhésion/interactions cellulaires
cycle cellulaire
développement
mecanotransduction
morphogenèse
signalisation
transduction du signal
ovulation
ovary
reproduction
meiosis
oocyte
fertility
Techniques biophysique
culture 3d
imagerie confocale
imagerie multiphotons
systemes in vitro
Modèles cellulaires souris, rat